Proteome profiling of neuroblastoma-derived exosomes reveal the expression of proteins potentially involved in tumor progression.

Neuroblastoma (NB) is the most common extracranial solid tumor in childhood, with grim prognosis in a half of patients. Exosomes are nanometer-sized membrane vesicles derived from the multivesicular bodies (MVBs) of the endocytic pathway and released by normal and neoplastic cells. Tumor-derived exo...

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Bibliographic Details
Main Authors: Danilo Marimpietri, Andrea Petretto, Lizzia Raffaghello, Annalisa Pezzolo, Cristina Gagliani, Carlo Tacchetti, Pierluigi Mauri, Giovanni Melioli, Vito Pistoia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3777909?pdf=render