A bone-specific adipogenesis pathway in fat-free mice defines key origins and adaptations of bone marrow adipocytes with age and disease

Bone marrow adipocytes accumulate with age and in diverse disease states. However, their origins and adaptations in these conditions remain unclear, impairing our understanding of their context-specific endocrine functions and relationship with surrounding tissues. In this study, by analyzing bone a...

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Bibliographic Details
Main Authors: Xiao Zhang, Hero Robles, Kristann L Magee, Madelyn R Lorenz, Zhaohua Wang, Charles A Harris, Clarissa S Craft, Erica L Scheller
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-08-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/66275