Novel RICTOR amplification harbouring entities: FISH validation of RICTOR amplification in tumour tissue after next-generation sequencing

Novel RICTOR amplification harbouring entities: FISH validation of RICTOR amplification in tumour tissue after next-generation sequencing

Abstract Alterations in mTOR signalling molecules, including RICTOR amplification, have been previously described in many cancers, particularly associated with poor prognosis. In this study, RICTOR copy number variation (CNV) results of diagnostic next-generation sequencing (NGS) were analysed in 42...

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Bibliographic Details
Main Authors: Dániel Sztankovics, Ildikó Krencz, Dorottya Moldvai, Titanilla Dankó, Ákos Nagy, Noémi Nagy, Gábor Bedics, András Rókusz, Gergő Papp, Anna-Mária Tőkés, Judit Pápay, Zoltán Sápi, Katalin Dezső, Csaba Bödör, Anna Sebestyén
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-46927-x

Internet

https://doi.org/10.1038/s41598-023-46927-x

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