Glucocorticoid agonists enhance retinal stem cell self-renewal and proliferation

Glucocorticoid agonists enhance retinal stem cell self-renewal and proliferation

Abstract Background Adult mammalian retinal stem cells (RSCs) readily proliferate, self-renew, and generate progeny that differentiate into all retinal cell types in vitro. RSC-derived progeny can be induced to differentiate into photoreceptors, making them a potential source for retinal cell transp...

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Bibliographic Details
Main Authors: Kenneth N. Grisé, Nelson X. Bautista, Krystal Jacques, Brenda L. K. Coles, Derek van der Kooy
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Stem Cell Research & Therapy
Subjects:
Stem cell
progenitor
Retina
Glucocorticoid
proliferation
Self-renewal
Online Access:https://doi.org/10.1186/s13287-021-02136-9

Internet

https://doi.org/10.1186/s13287-021-02136-9

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