Carboxypeptidase E modulates intestinal immune homeostasis and protects against experimental colitis in mice.

Carboxypeptidase E modulates intestinal immune homeostasis and protects against experimental colitis in mice.

Enteroendocrine cells (EEC) produce neuropeptides, which are crucially involved in the maintenance of the intestinal barrier. Hence, EEC dysfunction is suggested to be involved in the complex pathophysiology of inflammatory bowel disease (IBD), which is characterized by decreased intestinal barrier...

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Bibliographic Details
Main Authors: Florian Bär, Bandik Föh, René Pagel, Torsten Schröder, Heidi Schlichting, Misa Hirose, Susanne Lemcke, Antje Klinger, Peter König, Christian M Karsten, Jürgen Büning, Hendrik Lehnert, Klaus Fellermann, Saleh M Ibrahim, Christian Sina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4106776?pdf=render

Internet

http://europepmc.org/articles/PMC4106776?pdf=render

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