Therapeutic role of EGFR - Tyrosine kinase inhibitors in non-small cell lung cancer with leptomeningeal metastasis

Therapeutic role of EGFR - Tyrosine kinase inhibitors in non-small cell lung cancer with leptomeningeal metastasis

Leptomeningeal metastasis (LM) is a significant complication that advances fast and has a poor prognosis for patients with advanced non-small cell lung cancer (NSCLC) who have epidermal growth factor receptor (EGFR) mutations. Current therapies for LM are inconsistent and ineffective, and establishe...

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Bibliographic Details
Main Authors: Caiyan Jia, Qian Xu, Lu Zhao, Fanming Kong, Yingjie Jia
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Translational Oncology
Subjects:
Leptomeningeal metastasis
Epidermal growth factor receptor
EGFR tyrosine kinase inhibitors
Non-small cell lung cancer
Osimertinib
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523323002188

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http://www.sciencedirect.com/science/article/pii/S1936523323002188

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