The JNK signaling pathway in intervertebral disc degeneration

The JNK signaling pathway in intervertebral disc degeneration

Intervertebral disc degeneration (IDD) serves as the underlying pathology for various spinal degenerative conditions and is a primary contributor to low back pain (LBP). Recent studies have revealed a strong correlation between IDD and biological processes such as Programmed Cell Death (PCD), cellul...

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Bibliographic Details
Main Authors: Ganggang Liu, Lu Gao, Yuncai Wang, Xinsheng Xie, Xuejiao Gao, Xingjie Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
intervertebral disc degeneration (IDD)
JNK path
programmed cell death (PCD)
cellular senescence (CS)
cell proliferation, inflammation
extracellar matrix (ECM) degradation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2024.1423665/full

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https://www.frontiersin.org/articles/10.3389/fcell.2024.1423665/full

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