Initial evaluation of [18F]-FACBC for PET imaging of multiple myeloma

Initial evaluation of [18F]-FACBC for PET imaging of multiple myeloma

Abstract Rationale Multiple myeloma (MM) cells synthesize large amounts of paraproteins, making radiolabeled amino acids promising candidates for PET imaging of MM patients. Methods We compare tumor uptake of the two amino acid analogs [18F]-fluoroethyltyrosine and [18F]-FACBC in a MM xenograft mode...

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Bibliographic Details
Main Authors: Volker Morath, Michael Heider, Markus Mittelhäuser, Hannes Rolbieski, Jacob Stroh, Jérémie Calais, Matthias Eiber, Florian Bassermann, Wolfgang A. Weber
Format: Article
Language:English
Published: SpringerOpen 2022-01-01
Series:EJNMMI Research
Subjects:
FACBC
Fluciclovine
Multiple myeloma
Hematology
FET
PET
Online Access:https://doi.org/10.1186/s13550-022-00876-0

Internet

https://doi.org/10.1186/s13550-022-00876-0

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