Hepatocyte nuclear factor 1A (HNF1A) as a possible tumor suppressor in pancreatic cancer.

HNF1A (Hepatocyte nuclear factor 1 alpha) is a transcription factor that is known to regulate pancreatic differentiation and maintain homeostasis of endocrine pancreas. Recently, genome-wide association studies have implicated HNF1A as a susceptibility gene for pancreatic cancer. However, the functi...

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Bibliographic Details
Main Authors: Zhaofan Luo, Yanan Li, Huamin Wang, Jason Fleming, Min Li, Yaan Kang, Ran Zhang, Donghui Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4368635?pdf=render