Production and Secretion of Gelsolin by Both Human Macrophage- and Fibroblast-like Synoviocytes and GSN Modulation in the Synovial Fluid of Patients with Various Forms of Arthritis

Production and Secretion of Gelsolin by Both Human Macrophage- and Fibroblast-like Synoviocytes and GSN Modulation in the Synovial Fluid of Patients with Various Forms of Arthritis

Gelsolin (GSN) is an actin-binding protein involved in cell formation, metabolism and wound closure processes. Since this protein is known to play a role in arthritis, here we investigate how the synovial membrane with its specific synoviocytes contributes to the expression of GSN and how the amount...

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Bibliographic Details
Main Authors: Jessica Feldt, Martin Schicht, Jessica Welss, Kolja Gelse, Stefan Sesselmann, Michael Tsokos, Eileen Socher, Fabian Garreis, Thomas Müller, Friedrich Paulsen
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Biomedicines
Subjects:
arthritis
gelsolin
synovial fluid
synoviocytes
Online Access:https://www.mdpi.com/2227-9059/10/3/723

Internet

https://www.mdpi.com/2227-9059/10/3/723

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