A Defect in Influenza A Virus Particle Assembly Specific to Primary Human Macrophages

A Defect in Influenza A Virus Particle Assembly Specific to Primary Human Macrophages

ABSTRACT Influenza A virus (IAV) propagates efficiently in epithelial cells, its primary target in the respiratory tract. In contrast, productive infection of most IAV strains is either blocked or highly inefficient in macrophages. The exact nature of the defect in IAV replication in human macrophag...

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Bibliographic Details
Main Authors: Sukhmani Bedi, Takeshi Noda, Yoshihiro Kawaoka, Akira Ono
Format: Article
Language:English
Published: American Society for Microbiology 2018-11-01
Series:mBio
Subjects:
actin
influenza
macrophages
plasma membrane
virus assembly
Online Access:https://journals.asm.org/doi/10.1128/mBio.01916-18

Internet

https://journals.asm.org/doi/10.1128/mBio.01916-18

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