Efficient Synthesis and HPLC-Based Characterization for Developing Vanadium-48-Labeled Vanadyl Acetylacetonate as a Novel Cancer Radiotracer for PET Imaging

Efficient Synthesis and HPLC-Based Characterization for Developing Vanadium-48-Labeled Vanadyl Acetylacetonate as a Novel Cancer Radiotracer for PET Imaging

<i>Bis</i>(acetylacetonato)oxidovanadium(IV) [(VO(acac)<sub>2</sub>], generally known as vanadyl acetylacetonate, has been shown to be preferentially sequestered in malignant tissue. Vanadium-48 (<sup>48</sup>V) generated with a compact medical cyclotron has been...

Full description

Bibliographic Details
Main Authors: Brittany A. Broder, Mohammed Bhuiyan, Richard Freifelder, David A. Rotsch, Satish K. Chitneni, Marvin W. Makinen, Chin-Tu Chen
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Molecules
Subjects:
vanadium
vanadium-48
vanadyl acetylacetonate
high performance liquid chromatography (HPLC)
positron emission tomography (PET)
PET imaging
Online Access:https://www.mdpi.com/1420-3049/29/4/799

Internet

https://www.mdpi.com/1420-3049/29/4/799

Similar Items