High sporulation and overexpression of virulence factors in biofilms and reduced susceptibility to vancomycin and linezolid in recurrent Clostridium [Clostridioides] difficile infection isolates.

High sporulation and overexpression of virulence factors in biofilms and reduced susceptibility to vancomycin and linezolid in recurrent Clostridium [Clostridioides] difficile infection isolates.

Clostridium [Clostridioides] difficile infection (CDI) is one of the leading causes of diarrhea associated with medical care worldwide, and up to 60% of patients with CDI can develop a recurrent infection (R-CDI). A multi-species microbiota biofilm model of C. difficile was designed to evaluate the...

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Bibliographic Details
Main Authors: Laura Tijerina-Rodríguez, Licet Villarreal-Treviño, Simon D Baines, Rayo Morfín-Otero, Adrián Camacho-Ortíz, Samantha Flores-Treviño, Héctor Maldonado-Garza, Eduardo Rodríguez-Noriega, Elvira Garza-González
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0220671

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https://doi.org/10.1371/journal.pone.0220671

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