Evaluation of the ability of LL-37 to neutralise LPS in vitro and ex vivo.

<h4>Background</h4>Human cathelicidin LL-37 is a cationic antimicrobial peptide (AMP) which possesses a variety of activities including the ability to neutralise endotoxin. In this study, we investigated the role of LPS neutralisation in mediating LL-37's ability to inhibit Pseudomo...

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Bibliographic Details
Main Authors: Aaron Scott, Sinéad Weldon, Paul J Buchanan, Bettina Schock, Robert K Ernst, Danny F McAuley, Michael M Tunney, Chris R Irwin, J Stuart Elborn, Clifford C Taggart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22028895/pdf/?tool=EBI