Genetic Variation in ADAMTS13 is Related to VWF Levels, Atrial Fibrillation and Cerebral Ischemic Events

Genetic Variation in ADAMTS13 is Related to VWF Levels, Atrial Fibrillation and Cerebral Ischemic Events

Introduction ADAMTS13 cleaves von Willebrand factor (VWF) multimers into less active fragments. Both markers have been related to cardiovascular disease (CVD). We aimed to investigate the influence of ADAMTS13 single nucleotide polymorphisms (SNPs) on levels of ADAMTS13 and VWF, and CVD. Methods The...

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Main Authors: Ellen M. K. Warlo MD, Vibeke Bratseth MSc, PhD, Alf-Åge R. Pettersen MD, PhD, Pål Andre Holme MD, PhD, Harald Arnesen MD, PhD, Ingebjørg Seljeflot PhD, Trine B. Opstad MSc, PhD
Format: Article
Language:English
Published: SAGE Publishing 2022-12-01
Series:Clinical and Applied Thrombosis/Hemostasis
Online Access:https://doi.org/10.1177/10760296221141893

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https://doi.org/10.1177/10760296221141893

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