Production of Human Pluripotent Stem Cell-Derived Hepatic Cell Lineages and Liver Organoids: Current Status and Potential Applications

Liver disease is one of the leading causes of death worldwide, leading to the death of approximately 2 million people per year. Current therapies include orthotopic liver transplantation, however, donor organ shortage remains a great challenge. In addition, the development of novel therapeutics has...

Full description

Bibliographic Details
Main Authors: João P. Cotovio, Tiago G. Fernandes
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Bioengineering
Subjects:
Online Access:https://www.mdpi.com/2306-5354/7/2/36