HDL Cholesterol Efflux and Serum Cholesterol Loading Capacity Alterations Associate to Macrophage Cholesterol Accumulation in FH Patients with Achilles Tendon Xanthoma

HDL Cholesterol Efflux and Serum Cholesterol Loading Capacity Alterations Associate to Macrophage Cholesterol Accumulation in FH Patients with Achilles Tendon Xanthoma

Achilles tendon xanthoma (ATX) formation involves macrophage cholesterol accumulation within the tendon, similar to that occurring in atheroma. Macrophage cholesterol homeostasis depends on serum lipoprotein functions, namely the high-density lipoprotein (HDL) capacity to promote cell cholesterol ef...

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Bibliographic Details
Main Authors: Maria Pia Adorni, Marta Biolo, Francesca Zimetti, Marcella Palumbo, Nicoletta Ronda, Paolo Scarinzi, Paolo Simioni, Maria Giovanna Lupo, Nicola Ferri, Lorenzo Previato, Franco Bernini, Alberto Zambon
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:International Journal of Molecular Sciences
Subjects:
Achilles tendon
xanthoma
macrophage
HDL cholesterol efflux
serum cholesterol loading
Online Access:https://www.mdpi.com/1422-0067/23/15/8255

Internet

https://www.mdpi.com/1422-0067/23/15/8255

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