Network propagation-based prioritization of long tail genes in 17 cancer types

Abstract Background The diversity of genomic alterations in cancer poses challenges to fully understanding the etiologies of the disease. Recent interest in infrequent mutations, in genes that reside in the “long tail” of the mutational distribution, uncovered new genes with significant implications...

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Bibliographic Details
Main Authors: Hussein Mohsen, Vignesh Gunasekharan, Tao Qing, Montrell Seay, Yulia Surovtseva, Sahand Negahban, Zoltan Szallasi, Lajos Pusztai, Mark B. Gerstein
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-021-02504-x