NRF2 Mediates Cellular Resistance to Transformation, Radiation, and Inflammation in Mice

NRF2 Mediates Cellular Resistance to Transformation, Radiation, and Inflammation in Mice

Nuclear factor erythroid 2-related factor 2 (NRF2) is recognized as a master transcription factor that regulates expression of numerous detoxifying and antioxidant cytoprotective genes. In fact, models of NRF2 deficiency indicate roles not only in redox regulation, but also in metabolism, inflammato...

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Bibliographic Details
Main Authors: Dörthe Schaue, Ewa D. Micewicz, Josephine A. Ratikan, Keisuke S. Iwamoto, Erina Vlashi, J. Tyson McDonald, William H. McBride
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Antioxidants
Subjects:
Nrf2
NF-κB
ionizing radiation
immune polarization
Online Access:https://www.mdpi.com/2076-3921/11/9/1649

Internet

https://www.mdpi.com/2076-3921/11/9/1649

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