SPARC Controls Melanoma Cell Plasticity through Rac1.
Cell transition to a more aggressive mesenchymal-like phenotype is a hallmark of cancer progression that involves different steps and requires tightly regulated cell plasticity. SPARC (Secreted Protein Acidic and Rich in Cysteine) is a matricellular protein that promotes this transition in various m...
Główni autorzy: | , , , , , , |
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Format: | Artykuł |
Język: | English |
Wydane: |
Public Library of Science (PLoS)
2015-01-01
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Seria: | PLoS ONE |
Dostęp online: | http://europepmc.org/articles/PMC4527691?pdf=render |