SPARC Controls Melanoma Cell Plasticity through Rac1.

SPARC Controls Melanoma Cell Plasticity through Rac1.

Cell transition to a more aggressive mesenchymal-like phenotype is a hallmark of cancer progression that involves different steps and requires tightly regulated cell plasticity. SPARC (Secreted Protein Acidic and Rich in Cysteine) is a matricellular protein that promotes this transition in various m...

Full description

Bibliographic Details
Main Authors: Edgardo Salvatierra, Mariano J Alvarez, Claudia C Leishman, Elvia Rivas Baquero, Viviana P Lutzky, H Eduardo Chuluyan, Osvaldo L Podhajcer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4527691?pdf=render

Internet

http://europepmc.org/articles/PMC4527691?pdf=render

Similar Items