Quiescent fibroblasts exhibit high metabolic activity.

Many cells in mammals exist in the state of quiescence, which is characterized by reversible exit from the cell cycle. Quiescent cells are widely reported to exhibit reduced size, nucleotide synthesis, and metabolic activity. Much lower glycolytic rates have been reported in quiescent compared with...

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Bibliographic Details
Main Authors: Johanna M S Lemons, Xiao-Jiang Feng, Bryson D Bennett, Aster Legesse-Miller, Elizabeth L Johnson, Irene Raitman, Elizabeth A Pollina, Herschel A Rabitz, Joshua D Rabinowitz, Hilary A Coller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2958657?pdf=render