Gossypol Broadly Inhibits Coronaviruses by Targeting RNA‐Dependent RNA Polymerases

Gossypol Broadly Inhibits Coronaviruses by Targeting RNA‐Dependent RNA Polymerases

Abstract Outbreaks of coronaviruses (CoVs), especially severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), have posed serious threats to humans and animals, which urgently calls for effective broad‐spectrum antivirals. RNA‐dependent RNA polymerase (RdRp) plays an essential role in viral RN...

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Bibliographic Details
Main Authors: Wenjing Wang, Wenkang Li, Zhiyuan Wen, Chong Wang, Weilong Liu, Yufang Zhang, Juncheng Liu, Tianze Ding, Lei Shuai, Gongxun Zhong, Zhigao Bu, Lingbo Qu, Maozhi Ren, Fuguang Li
Format: Article
Language:English
Published: Wiley 2022-12-01
Series:Advanced Science
Subjects:
coronavirus
gossypol
natural product
RNA‐dependent RNA polymerase
SARS‐CoV‐2
Online Access:https://doi.org/10.1002/advs.202203499

Internet

https://doi.org/10.1002/advs.202203499

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