Pharmacokinetics of florfenicol and its metabolite florfenicol amine in the plasma, urine, and feces of fattening male donkeys following single oral administration

Pharmacokinetics of florfenicol and its metabolite florfenicol amine in the plasma, urine, and feces of fattening male donkeys following single oral administration

Florfenicol (FF) is a commonly used antibacterial agent in animals. We investigated the pharmacokinetics of FF and its metabolite florfenicol amine (FFA) in donkeys. Donkeys were administered FF (30 mg/kg bodyweight, p.o.). Pharmacokinetic parameters were calculated using a non-compartmental model....

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Bibliographic Details
Main Authors: Shijie Liu, Yanxin Guo, Honglei Qu, Yanjie Dong, Shancang Zhao, Tianze Fu, Ruifen Kang, Jie Cheng, Shimeng Huang, Lihong Zhao, Qiugang Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Veterinary Science
Subjects:
florfenicol
florfenicol amine
pharmacokinetics
donkey
urinary excretion
antibiotic
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2023.1314029/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2023.1314029/full

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