Mice Mutated in the Third Fibronectin Domain of L1 Show Enhanced Hippocampal Neuronal Cell Death, Astrogliosis and Alterations in Behavior

Mice Mutated in the Third Fibronectin Domain of L1 Show Enhanced Hippocampal Neuronal Cell Death, Astrogliosis and Alterations in Behavior

Adhesion molecules play major roles in cell proliferation, migration, survival, neurite outgrowth and synapse formation during nervous system development and in adulthood. The neural cell adhesion molecule L1 contributes to these functions during development and in synapse formation and synaptic pla...

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Bibliographic Details
Main Authors: Ludovica Congiu, Viviana Granato, Igor Jakovcevski, Ralf Kleene, Luciana Fernandes, Sandra Freitag, Matthias Kneussel, Melitta Schachner, Gabriele Loers
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Biomolecules
Subjects:
L1CAM
hippocampus
neuronal cell death
astrogliosis
behavior
Online Access:https://www.mdpi.com/2218-273X/13/5/776

Internet

https://www.mdpi.com/2218-273X/13/5/776

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