Network analysis and experimental pharmacology study explore the protective effects of Isoliquiritigenin on 5-fluorouracil-Induced intestinal mucositis

Network analysis and experimental pharmacology study explore the protective effects of Isoliquiritigenin on 5-fluorouracil-Induced intestinal mucositis

5-fluorouracil (5-FU) is one of the most widely used chemotherapy drugs for malignant tumors. However, intestinal mucositis caused by 5-FU is a severe dose-limiting toxic effect and even leads to treatment interruption. Isoliquiritigenin (ISL) is one of the main active compounds of licorice, which i...

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Bibliographic Details
Main Authors: Yi-fan Liao, Feng-lin Luo, Shan-shan Tang, Jing-wei Huang, Ying Yang, Shuang Wang, Tang-yu Jiang, Qiong Man, Sha Liu, Yi-ying Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Pharmacology
Subjects:
5-fluorouracil
intestinal mucositis
Isoliquiritigenin
inflammatory mediator
network analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1014160/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.1014160/full

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