Identification of Genetic Alterations in Rapid Progressive Glioblastoma by Use of Whole Exome Sequencing

Identification of Genetic Alterations in Rapid Progressive Glioblastoma by Use of Whole Exome Sequencing

Background: Glioblastoma poses an inevitable threat to patients despite aggressive therapy regimes. It displays a great level of molecular heterogeneity and numerous substitutions in several genes have been documented. Next-generation sequencing techniques have identified various molecular signature...

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Bibliographic Details
Main Authors: Imran Khan, Esra Büşra Işık, Sadaf Mahfooz, Asif M. Khan, Mustafa Aziz Hatiboglu
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Diagnostics
Subjects:
whole exome sequencing
glioblastoma
cancer
tumor mutation burden
genetic screening
genetic signature
Online Access:https://www.mdpi.com/2075-4418/13/6/1017

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https://www.mdpi.com/2075-4418/13/6/1017

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