Network pharmacology and experimental validation methods to reveal the active compounds and hub targets of Curculigo orchioides Gaertn in rheumatoid arthritis

Abstract Background Rheumatoid arthritis (RA) is an autoimmune disease that can lead to joint destruction and deformity. Curculigo orchioides Gaertn (CO) was previously revealed to play a significant role in RA treatment. However, the main active ingredients and molecular mechanisms of CO in regulat...

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Bibliographic Details
Main Authors: Xia Liu, Mingchun Huang, Lijuan Wang, Jie Li, Weihui Wu, Qin Wang
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-023-04352-w