Generation of protective immunity against Orientia tsutsugamushi infection by immunization with a zinc oxide nanoparticle combined with ScaA antigen

Generation of protective immunity against Orientia tsutsugamushi infection by immunization with a zinc oxide nanoparticle combined with ScaA antigen

Abstract Background Zinc oxide nanoparticle (ZNP) has been applied in various biomedical fields. Here, we investigated the usage of ZNP as an antigen carrier for vaccine development by combining a high affinity peptide to ZNP. Results A novel zinc oxide-binding peptide (ZBP), FPYPGGDA, with high aff...

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Bibliographic Details
Main Authors: Na-Young Ha, Hyun Mu Shin, Prashant Sharma, Hyun Ah Cho, Chan-Ki Min, Hong-il Kim, Nguyen Thi Hai Yen, Jae-Seung Kang, Ik-Sang Kim, Myung-Sik Choi, Young Keun Kim, Nam-Hyuk Cho
Format: Article
Language:English
Published: BMC 2016-11-01
Series:Journal of Nanobiotechnology
Subjects:
Zinc oxide nanoparticle
ZnO binding peptide
Scrub typhus
Vaccine
Online Access:http://link.springer.com/article/10.1186/s12951-016-0229-2

Internet

http://link.springer.com/article/10.1186/s12951-016-0229-2

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