Disturbed flow regulates protein disulfide isomerase A1 expression via microRNA-204

Disturbed flow regulates protein disulfide isomerase A1 expression via microRNA-204

Redox processes can modulate vascular pathophysiology. The endoplasmic reticulum redox chaperone protein disulfide isomerase A1 (PDIA1) is overexpressed during vascular proliferative diseases, regulating thrombus formation, endoplasmic reticulum stress adaptation, and structural remodeling. However,...

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Bibliographic Details
Main Authors: Leonardo Y. Tanaka, Sandeep Kumar, Lucas F. Gutierre, Celso Magnun, Daniela Kajihara, Dong-Won Kang, Francisco R. M. Laurindo, Hanjoong Jo
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Physiology
Subjects:
protein disulfide isomerase
microRNA
vascular smooth muscle cell
disturbed flow
atherosclerosis
phenotype switch
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2024.1327794/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2024.1327794/full

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