A role for foregut tyrosine metabolism in glucose tolerance

A role for foregut tyrosine metabolism in glucose tolerance

Objective: We hypothesized that DA and L-DOPA derived from nutritional tyrosine and the resultant observed postprandial plasma excursions of L-DOPA and DA might affect glucose tolerance via their ability to be taken-up by beta cells and inhibit glucose-stimulated β-cell insulin secretion. Methods: T...

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Bibliographic Details
Main Authors: Judith Korner, Gary W. Cline, Mark Slifstein, Pasquale Barba, Gina R. Rayat, Gerardo Febres, Rudolph L. Leibel, Antonella Maffei, Paul E. Harris
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877819301218

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http://www.sciencedirect.com/science/article/pii/S2212877819301218

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