Looking for A Place for Dose-Dense TMZ Regimens in GBM Patients: An Experience with MGMT Exploratory Evaluation

Looking for A Place for Dose-Dense TMZ Regimens in GBM Patients: An Experience with MGMT Exploratory Evaluation

Prolonged exposure to temozolomide (TMZ) could improve clinical outcomes in recurrent glioblastoma multiforme (GBM) patients. We previously developed a dose-dense regimen of TMZ in a phase II study (180 mg/m2 from days 1 to 5 every two weeks). A retrospective analysis of patients with macroscopic re...

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Bibliographic Details
Main Authors: Luca Napoleoni, Alessio Cortellini, Katia Cannita, Alessandro Parisi, Antonella Dal Mas, Giuseppe Calvisi, Olga Venditti, Paola Lanfiuti Baldi, Valentina Cocciolone, Alessandro Ricci, Corrado Ficorella
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Bioengineering
Subjects:
glioblastoma multiforme
dose-dense
temozolomide
MGMT
Online Access:https://www.mdpi.com/2306-5354/6/1/11

Internet

https://www.mdpi.com/2306-5354/6/1/11

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