Exogenous Hydrogen Sulfide Activates PI3K/Akt/eNOS Pathway to Improve Replicative Senescence in Human Umbilical Vein Endothelial Cells

Background. Endothelial cell senescence is one of the key mechanistic factors in the pathogenesis of atherosclerosis. In terms of molecules, the phosphatidylinositol 3-kinase/protein kinase B/endothelial nitric oxide synthase (PI3K/Akt/eNOS) signaling plays an important role in the prevention and co...

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Bibliographic Details
Main Authors: Haiming Niu, Jianwei Li, Hongkai Liang, Guishen Wu, Miaolian Chen
Format: Article
Language:English
Published: Hindawi Limited 2023-01-01
Series:Cardiology Research and Practice
Online Access:http://dx.doi.org/10.1155/2023/7296874