Cephalometric landmark detection without X-rays combining coordinate regression and heatmap regression

Abstract Fully automated techniques using convolutional neural networks for cephalometric landmark detection have recently advanced. However, all existing studies have adopted X-rays. The problem of direct exposure of patients to X-ray radiation remains unsolved. We propose a model for detecting cep...

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Main Authors: Kaisei Takahashi, Yui Shimamura, Chie Tachiki, Yasushi Nishii, Masafumi Hagiwara
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-46919-x
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author Kaisei Takahashi
Yui Shimamura
Chie Tachiki
Yasushi Nishii
Masafumi Hagiwara
author_facet Kaisei Takahashi
Yui Shimamura
Chie Tachiki
Yasushi Nishii
Masafumi Hagiwara
author_sort Kaisei Takahashi
collection DOAJ
description Abstract Fully automated techniques using convolutional neural networks for cephalometric landmark detection have recently advanced. However, all existing studies have adopted X-rays. The problem of direct exposure of patients to X-ray radiation remains unsolved. We propose a model for detecting cephalometric landmarks using only facial profile images without X-rays. First, the model estimates the landmark coordinates using the features of facial profile images through high-resolution representation learning. Second, considering the spatial relationship of the landmarks, the model refines the estimated coordinates. The estimated coordinates are input into fully connected networks to improve the accuracy. During the experiment, a total of 2000 facial profile images collected from 2000 female patients were used. Experiments results suggested that the proposed method may perform at a level equal to or potentially better than existing methods using cephalograms. We obtained an MRE of 0.61 mm for the test data and a mean detection rate of 98.20% within 2 mm. Our proposed two-stage learning method enables a highly accurate estimation of the landmark positions using only facial profile images. The results indicate that X-rays may not be required when detecting cephalometric landmarks.
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spelling doaj.art-d94e0e0b9cfe4a7db3696bca812cb8af2023-11-19T12:56:52ZengNature PortfolioScientific Reports2045-23222023-11-0113111310.1038/s41598-023-46919-xCephalometric landmark detection without X-rays combining coordinate regression and heatmap regressionKaisei Takahashi0Yui Shimamura1Chie Tachiki2Yasushi Nishii3Masafumi Hagiwara4Department of Information and Computer Science, Faculty of Science and Technology, Keio UniversityDepartment of Orthodontics, Tokyo Dental CollegeDepartment of Orthodontics, Tokyo Dental CollegeDepartment of Orthodontics, Tokyo Dental CollegeDepartment of Information and Computer Science, Faculty of Science and Technology, Keio UniversityAbstract Fully automated techniques using convolutional neural networks for cephalometric landmark detection have recently advanced. However, all existing studies have adopted X-rays. The problem of direct exposure of patients to X-ray radiation remains unsolved. We propose a model for detecting cephalometric landmarks using only facial profile images without X-rays. First, the model estimates the landmark coordinates using the features of facial profile images through high-resolution representation learning. Second, considering the spatial relationship of the landmarks, the model refines the estimated coordinates. The estimated coordinates are input into fully connected networks to improve the accuracy. During the experiment, a total of 2000 facial profile images collected from 2000 female patients were used. Experiments results suggested that the proposed method may perform at a level equal to or potentially better than existing methods using cephalograms. We obtained an MRE of 0.61 mm for the test data and a mean detection rate of 98.20% within 2 mm. Our proposed two-stage learning method enables a highly accurate estimation of the landmark positions using only facial profile images. The results indicate that X-rays may not be required when detecting cephalometric landmarks.https://doi.org/10.1038/s41598-023-46919-x
spellingShingle Kaisei Takahashi
Yui Shimamura
Chie Tachiki
Yasushi Nishii
Masafumi Hagiwara
Cephalometric landmark detection without X-rays combining coordinate regression and heatmap regression
Scientific Reports
title Cephalometric landmark detection without X-rays combining coordinate regression and heatmap regression
title_full Cephalometric landmark detection without X-rays combining coordinate regression and heatmap regression
title_fullStr Cephalometric landmark detection without X-rays combining coordinate regression and heatmap regression
title_full_unstemmed Cephalometric landmark detection without X-rays combining coordinate regression and heatmap regression
title_short Cephalometric landmark detection without X-rays combining coordinate regression and heatmap regression
title_sort cephalometric landmark detection without x rays combining coordinate regression and heatmap regression
url https://doi.org/10.1038/s41598-023-46919-x
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