Tamoxifen Rechallenge Decreases Metastatic Potential but Increases Cell Viability and Clonogenicity in a Tamoxifen-Mediated Cytotoxicity-Resistant Subline of Human Breast MCF7 Cancer Cells
BackgroundDrug resistance is frequently found in estrogen receptor–positive (ER+) breast cancer patients during and after prolonged tamoxifen treatment. Although tamoxifen rechallenge has been proposed for treating recurrent breast tumors, the clinical benefit of this treatment is still controversia...
Huvudupphovsmän: | , , |
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Materialtyp: | Artikel |
Språk: | English |
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Frontiers Media S.A.
2020-06-01
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Serie: | Frontiers in Cell and Developmental Biology |
Ämnen: | |
Länkar: | https://www.frontiersin.org/article/10.3389/fcell.2020.00485/full |