IL-37 alleviates liver granuloma caused by Schistosoma japonicum infection by inducing alternative macrophage activation

IL-37 alleviates liver granuloma caused by Schistosoma japonicum infection by inducing alternative macrophage activation

Abstract Background Hepatic macrophages regulate liver granuloma formation and fibrosis caused by infection with Schistosoma japonicum, with the manner of regulation dependent on macrophage activation state. Interleukin (IL)-37 may have immunomodulatory effects on macrophages. However, whether IL-37...

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Bibliographic Details
Main Authors: Cuiping Ren, Fengchun Liu, Chen Xing, Ruyu Zhao, Xiaoxue Tang, Miao Liu, Wenda Gao, Jijia Shen
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Parasites & Vectors
Subjects:
Schistosoma japonicum
IL-37
Liver granuloma
Macrophages
AMPK
Online Access:https://doi.org/10.1186/s13071-022-05420-6

Internet

https://doi.org/10.1186/s13071-022-05420-6

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