β-Cell Autophagy Pathway and Endoplasmic Reticulum Stress Regulating-Role of Liposomal Curcumin in Experimental Diabetes Mellitus: A Molecular and Morphometric Study

β-Cell Autophagy Pathway and Endoplasmic Reticulum Stress Regulating-Role of Liposomal Curcumin in Experimental Diabetes Mellitus: A Molecular and Morphometric Study

Background: Autophagy can confer protection to pancreatic β-cells from the harmful effects of metabolic stress by delaying apoptosis. Curcumin (CUR) alleviates oxidative and endoplasmic reticulum (ER) stress, activates autophagy, reduces inflammation, and decreases β-cell damage in type I diabetes....

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Bibliographic Details
Main Authors: Safaa I. Khater, Mohamed F. Dowidar, Aya E. Abdel-Aziz, Tarek Khamis, Naief Dahran, Leena S. Alqahtani, Mohamed M. M. Metwally, Al-Sayed Al-Hady Abd-Elrahamn, Mohammed Alsieni, Manal E. Alosaimi, Maram H. Abduljabbar, Amany Abdel-Rahman Mohamed
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Antioxidants
Subjects:
autophagy
ER stress
miRNA
pancreatic β-cells
immunohistochemical reactivity
Online Access:https://www.mdpi.com/2076-3921/11/12/2400

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https://www.mdpi.com/2076-3921/11/12/2400

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