Genetic deletion of Bco2 and Isx establishes a golden mouse model for carotenoid research

Objective: Low plasma levels of carotenoids are associated with mortality and chronic disease states. Genetic studies in animals revealed that the tissue accumulation of these dietary pigments is associated with the genes encoding β-carotene oxygenase 2 (BCO2) and the scavenger receptor class B type...

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Bibliographic Details
Main Authors: Linda D. Thomas, Srinivasagan Ramkumar, Marcin Golczak, Johannes von Lintig
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Molecular Metabolism
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877823000765