The global change of gene expression pattern caused by PTEN mutation affects the prognosis of glioblastoma

Glioblastoma (GBM), an aggressive primary tumor, is common in humans, accounting for 12–15% of all intracranial tumors, and has median survival of fewer than 15 months. Since a growing body of evidence suggests that conventional drugs are ineffective against GBM, our goal is to find emerging therapi...

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Bibliographic Details
Main Authors: Shengjun Zhou, Haifeng Wang, Yi Huang, Yiwen Wu, Zhiqing Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.952521/full