Human CST Facilitates Genome-wide RAD51 Recruitment to GC-Rich Repetitive Sequences in Response to Replication Stress

Human CST Facilitates Genome-wide RAD51 Recruitment to GC-Rich Repetitive Sequences in Response to Replication Stress

Show other versions (1)

The telomeric CTC1/STN1/TEN1 (CST) complex has been implicated in promoting replication recovery under replication stress at genomic regions, yet its precise role is unclear. Here, we report that STN1 is enriched at GC-rich repetitive sequences genome-wide in response to hydroxyurea (HU)-induced rep...

Full description

Bibliographic Details
Main Authors: Megan Chastain, Qing Zhou, Olga Shiva, Leanne Whitmore, Pingping Jia, Xueyu Dai, Chenhui Huang, Maria Fadri-Moskwik, Ping Ye, Weihang Chai
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Cell Reports
Subjects:
CTC1/STN1/TEN1
replication stress
RAD51
genome stability
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716308464

Internet

http://www.sciencedirect.com/science/article/pii/S2211124716308464

Similar Items