Assessing Creatine Supplementation for Neuroprotection against Perinatal Hypoxic-Ischaemic Encephalopathy: A Systematic Review of Perinatal and Adult Pre-Clinical Studies

Assessing Creatine Supplementation for Neuroprotection against Perinatal Hypoxic-Ischaemic Encephalopathy: A Systematic Review of Perinatal and Adult Pre-Clinical Studies

There is an important unmet need to develop interventions that improve outcomes of hypoxic-ischaemic encephalopathy (HIE). Creatine has emerged as a promising neuroprotective agent. Our objective was to systematically evaluate the preclinical animal studies that used creatine for perinatal neuroprot...

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Bibliographic Details
Main Authors: Nhi Thao Tran, Sharmony B. Kelly, Rod J. Snow, David W. Walker, Stacey J. Ellery, Robert Galinsky
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cells
Subjects:
neuroprotection
hypoxic ischaemic encephalopathy
brain injury
perinatal encephalopathy
creatine
phosphocreatine
Online Access:https://www.mdpi.com/2073-4409/10/11/2902

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https://www.mdpi.com/2073-4409/10/11/2902

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