Intravenous immunoglobulin treatment in childhood encephalitis (IgNiTE): a randomised controlled trial

Intravenous immunoglobulin treatment in childhood encephalitis (IgNiTE): a randomised controlled trial

Objective To investigate whether intravenous immunoglobulin (IVIG) improves neurological outcomes in children with encephalitis when administered early in the illness.Design Phase 3b multicentre, double-blind, randomised placebo-controlled trial.Setting Twenty-one hospitals in the UK.Participants Ch...

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Main Authors: Simon Nadel, Claire Cameron, David Pace, Rachel Kneen, Matilda Hill, Federico Martinón-Torres, Tom Solomon, Mandy Wan, Angela Vincent, Michael Absoud, Patrick Waters, Manish Sadarangani, Xinxue Liu, Andrew J Pollard, Sanjay Bhate, Ly-Mee Yu, John Alexander, Sarosh Irani, David Kerr, Andrew Collinson, Ava Easton, William Whitehouse, Ming Lim, Emma Plested, Paul Heath, Dominic Smith, Michael Pike, Adilia Warris, Anna Riddell, Paddy McMaster, Simon Kerridge, Louise Willis, Christopher Clark, Victoria Gray, Jay Shetty, John Livingston, Kling Chong, Vishal Mehta, Charles Warlow, Jo Haviland, Alice Jollands, Shakeel Herwitker, Daniel O’Connor, Yama Mujadidi, Lauren Burke, Mildred Iro, Sagida Bibi, Liberty Cantrell, Mike Pike, Chris A. Clark, Sophie Bradshaw, Svetlana Milca, Mike Bale, Sonia Bale, Alan Percival, Meryn Voysey, Amy Beveridge, Amber Thompson, Parvinder Alley, Archana Desurkar, Elma Stephen, Steve Welch, Kayal Vijayakumar, Leena Mewasingh, Christian de Goede
Format: Article
Language:English
Published: BMJ Publishing Group 2023-11-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/13/11/e072134.full

Internet

https://bmjopen.bmj.com/content/13/11/e072134.full

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