Indoleamine 2,3-dioxygenase 1 inhibitor Epacadostat combined with IFN-γ induces apoptosis of triple-negative breast cancer cell lines

Objective To investigate the effect of IFN-γ combined with IDO1 inhibitor Epacadostat(Epa) on the treatment of triple-negative breast cancer cell lines 4T1 and MDA-MB-231. Methods Following treatment with IFN-γ, Epa or IFN-γ combined with Epa on 4T1 and MDA-MB-231 cells for 48 h, the apoptosis of ce...

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Bibliographic Details
Main Author: HU Qing-qing, LU Yan
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2020-05-01
Series:Jichu yixue yu linchuang
Subjects:
Online Access:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a190886.pdf