The generalized relative pairs IBD distribution: its use in the detection of linkage

I introduce a novel approach to derive the distribution of disease affectional status given alleles identical by descent (IBD) sharing through ITO method. My approach tremendously simplifies the calculation of the affectional status distribution compared to the conventional method which requires the...

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Bibliographic Details
Main Author: Quan Zou
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Public Health
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpubh.2016.00259/full