Efficient CRISPR/Cas9-mediated gene disruption in the tetraploid protist Giardia intestinalis

Efficient CRISPR/Cas9-mediated gene disruption in the tetraploid protist Giardia intestinalis

CRISPR/Cas9-mediated genome editing has become an extremely powerful technique used to modify gene expression in many organisms, including parasitic protists. Giardia intestinalis, a protist parasite that infects approximately 280 million people around the world each year, has been eluding the use o...

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Bibliographic Details
Main Authors: Vendula Horáčková, Luboš Voleman, Kari D. Hagen, Markéta Petrů, Martina Vinopalová, Filip Weisz, Natalia Janowicz, Lenka Marková, Alžběta Motyčková, Vladimíra Najdrová, Pavla Tůmová, Scott C. Dawson, Pavel Doležal
Format: Article
Language:English
Published: The Royal Society 2022-04-01
Series:Open Biology
Subjects:
Giardia
CRISPR/Cas9
gene knockout
multiploid
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.210361

Internet

https://royalsocietypublishing.org/doi/10.1098/rsob.210361

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