DWV 3C Protease Uncovers the Diverse Catalytic Triad in Insect RNA Viruses

ABSTRACT Deformed wing virus (DWV) is the most prevalent Iflavirus that is infecting honey bees worldwide. However, the mechanisms of its infection and replication in host cells are poorly understood. In this study, we analyzed the structure and function of DWV 3C protease (3Cpro), which is necessar...

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Bibliographic Details
Main Authors: Xuye Yuan, Tatsuhiko Kadowaki
Format: Article
Language:English
Published: American Society for Microbiology 2022-06-01
Series:Microbiology Spectrum
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00068-22