Extrarenal manifestations of complement mediated thrombotic microangiopathies

Extrarenal manifestations of complement mediated thrombotic microangiopathies

Thrombotic microangiopathies (TMA) are rare but severe disorders, characterized by endothelial cell activation and thrombus formation leading to hemolytic anemia, thrombocytopenia and organ failure. Complement over activation in combination with defects in its regulation is described in an increasin...

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Bibliographic Details
Main Authors: Johannes eHofer, Alejandra eRosales, Caroline eFischer, Thomas eGiner
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Pediatrics
Subjects:
complement
aHUS
TMA
extrarenal TMA
neurovascular complications
cardiovascular complication
Online Access:http://journal.frontiersin.org/Journal/10.3389/fped.2014.00097/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fped.2014.00097/full

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