Polymorphisms of Cytochromes P450 and Glutathione S-Transferases Synergistically Modulate Risk for Parkinson’s Disease
BackgroundEnvironmental substances such as pesticides are well-known in link with Parkinson’s disease (PD) risk. Enzymes including cytochromes P450 (CYPs), esterases and glutathione S-transferases (GSTs) are responsible for the xenobiotic metabolism and may functionally compensate each other for sub...
Main Authors: | Hui-Hui Fan, Bao-Qing Li, Ke-Yun Wu, Hai-Dan Yan, Meng-Jie Gu, Xing-Hao Yao, Hao-Jia Dong, Xiong Zhang, Jian-Hong Zhu |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-04-01
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Series: | Frontiers in Aging Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fnagi.2022.888942/full |
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