Adaptive and Innate Cytotoxic Effectors in Chronic Lymphocytic Leukaemia (CLL) Subjects with Stable Disease

Adaptive and Innate Cytotoxic Effectors in Chronic Lymphocytic Leukaemia (CLL) Subjects with Stable Disease

Chronic lymphocytic leukaemia (CLL) is characterised by the expansion of a neoplastic mature B cell clone. CLL clinical outcome is very heterogeneous, with some subjects never requiring therapy and some showing an aggressive disease. Genetic and epigenetic alterations and pro-inflammatory microenvir...

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Bibliographic Details
Main Authors: Valentina Rubino, Flavia Carriero, Anna Teresa Palatucci, Angela Giovazzino, Stefania Leone, Valerio Nicolella, Martina Calabrò, Rosangela Montanaro, Vincenzo Brancaleone, Fabrizio Pane, Federico Chiurazzi, Giuseppina Ruggiero, Giuseppe Terrazzano
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
chronic lymphocytic leukaemia
HLA class I molecules
cytotoxic T cells
NK cells
immune activation profile
Online Access:https://www.mdpi.com/1422-0067/24/11/9596

Internet

https://www.mdpi.com/1422-0067/24/11/9596

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