NFATc1 marks articular cartilage progenitors and negatively determines articular chondrocyte differentiation

NFATc1 marks articular cartilage progenitors and negatively determines articular chondrocyte differentiation

The origin and differentiation mechanism of articular chondrocytes remain poorly understood. Broadly, the difference in developmental mechanisms of articular and growth-plate cartilage is still less elucidated. Here, we identified that the nuclear factor of activated T-cells cytoplasmic 1 (NFATc1) i...

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Bibliographic Details
Main Authors: Fan Zhang, Yuanyuan Wang, Ying Zhao, Manqi Wang, Bin Zhou, Xianpeng Ge
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-02-01
Series:eLife
Subjects:
Articular cartilage
articular chondrocyte
progenitor cells
differentiation
transcriptional factor
NFATc1
Online Access:https://elifesciences.org/articles/81569

Internet

https://elifesciences.org/articles/81569

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