Autoinflammation in Syndromic Hidradenitis Suppurativa: The Role of AIM2

Autoinflammation in Syndromic Hidradenitis Suppurativa: The Role of AIM2

Background: AIM2 is a key cytoplasmatic pathogen-sensor that detects foreign DNA from viruses and bacteria; it can also recognize damaged or anomalous presence of DNA, promoting inflammasome assembly and activation with the secretion of IL-1β, thus sustaining a chronic inflammatory state, potentiall...

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Bibliographic Details
Main Authors: Chiara Moltrasio, Rachele Cagliani, Manuela Sironi, Mario Clerici, Chiara Pontremoli, Carlo Alberto Maronese, Paola Maura Tricarico, Sergio Crovella, Angelo Valerio Marzano
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Vaccines
Subjects:
innate immunity
AIM2
autoinflammation
hidradenitis suppurativa
syndromic autoinflammatory skin diseases
Online Access:https://www.mdpi.com/2076-393X/11/1/162

Internet

https://www.mdpi.com/2076-393X/11/1/162

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